The Vikings Set Sail Through Endorphina - 1792 Words

Blog 25 – The Vikings set sail through Endorphina Big time slot games are appearing everywhere you look this October. It seems the industry’s major developers have been enduring some late nights to create the games that are set to light up online casinos this autumn. Not to be a name to miss out on all the action, Endorphina has recently unveiled its latest creation. Taking inspirations from the days of Nordic Vikings, The Vikings is an impressive new title that is all set to unleash a brand new level of innovation. Back during Q1 2015, a small little game was unveiled at the Amsterdam Super Show. At the time this title from Endorphina impressed those who saw it, but it was by no means a mainstream attraction. However, as time passed†¦show more content†¦Available through instant play, The Vikings is a game that can be played on any device that has online casino access potential. Bonus Rounds and Free Spins What The Vikings does is take players on a visual journey around frozen northern Europe, so when you play this game be ready to put your game face on. Epic prizes are up for grabs should you be able to navigate your way through the games icy landscapes. Beautiful on the eye, the backdrop and reels co-exist seamlessly within The Vikings. When playing players will want to keep an eye out for the classic Viking ship that operates as the games wild symbol. In a clever game twist there is a second wild symbol in the form of a dragonhead, land either and your chances of winning big grows. The skull and sword symbol works as the games scatter symbol, so if you look past its terrifying nature, its sight will become much more appreciated in the midst of a game session. Reason being that these symbols are a player’s gateway into the heart racing bonus rounds. If all the above hasn’t got you chomping at the bit to play The Vikings, then this will be the kicker, as you can stack ac tually stack wilds to send your profits through the roof. The Vikings are here! It has been one of the most long awaited games it slots history. Since players first set eyes on it earlier this year it seems like the countdown was well and truly on. The Vikings is a game that has big shoes to fill and it seems to

Winnipeg General Strike Free Essays

The Winnipeg General Strike was a landmark in North America. The strike officially began on May 15th, 1919 at 11:00 AM and continued until late June, 1919, and approximately 35, 000 workers, basically the entire workforce of Winnipeg, walked off their jobs, risking their entire lives (Naylor, 2009). This strike has been one of the most studied historic moments in Canadian history. We will write a custom essay sample on Winnipeg General Strike or any similar topic only for you Order Now The General Strike had been brewing for many years prior to 1919, a large series of circumstances contributed to the strike, from international to local (Beszterda, 1975). The strike began in the beginning of May, 1919, after months of labor negotiations the workforce finally had enough and the strike began. The metalworkers were next to participate the strike, the employers of the main factories in the town refused to negotiate their contract. There was a committee that was composed of 1,000 manufactures, bankers, and politicians; they called themselves the Citizens Committee. The Winnipeg General Strike was caused by many reasons. One reason was the immediate reasons for the building of trades and metal workers going on strike for better wages and to improve the conditions that they worked in daily. The workers were payed a low wage and worked in horrible conditions that would automatically be condemned today. The money that they worked extremely hard for made it difficult to leave comfortably, as many people do today. The sweep of the strike involved non-unionzed workers as well, which arose from problems with World War 1. They sacrificed years of high expectations suring the war and its aftermath were greeted with high unemployment instead, an industrial turndown, and inflation. The tight labour market had led to an increase in unions, the success of the Russion Revolution in 1917 had led not only to an increase in ideas, but it also provoked a fear on the part of those in authority. (Munroe, 2010) The One Big Union was a major part of the strike. They did not organize or lead the 1919 Winnipeg General Strike, although its history was closely intertwined with that of the strike. Their radical ideas were getting warm response from many trade unionists. Once the delegates from western Canada unions arrived in Calgary for the meeting in the spring, they were no longer interested in fixing the Trades and Labor Congress. By moving to create the One Big Union, the Candians in the west had created many enimies for themselves, the business world, government officials, and all the craft unions all felt threated by the One Big Union. Spring of 1919, the newly formed Winnipeg Building Trades Council opened their doors for negotiations with their employer, the Winnipeg Builders Exchange. The workers were looking for increase in pay that would allow them to regain what they had lost to the war inflation. Builders stated that without the increase in construction, they could not afford to pay the higher wages that were demanded. Once this negoation was over, the employers agreed to a â€Å"take-it-or-leave-it† approach, stating that if they did not like the wages, then they did not do it and it was over. In results of fearing that the strike would spread to other cities, Senator Robertson was ordered to mediate the dispute and make a final ruling. Once both sides have been heard, he decided that the strikers and the City Council to accept the employee’s proposal. Once they learned of their success, they knew for sure that they would be using striking again in the future (Wikipedia, 2010). After the strike, the metal workers finally received the pay increase they were fighting for and went back to work satisfied with the outcome from the Winnipeg Strike. Some of the workers were not so lucky, they were thrown into jail for the reckless behavior they exhibited during the strike. Seven of the strike leaders were thrown into jail for conspiracy to overthrow the government, they were imprisoned for two years. They won 11 seats on the provincial election in Manitoba, four of them were the strike leaders. After 20 years, collective bargaining was finally looked at again in Canada. Due to the fact that nobody was working and the majority of the workforce were participating in the General Strike, Winnipeg’s economy went into decline. (Munroe, 2010). The effects from these outcomes are still in effect today. We are still receiving higher wages yearly. Minimum wage standards keep increasing at a constant in all provinces per year. This strike may have caused the working conditions today to be as good as what they are. If people hadn’t fought years ago for this then employers today would still be trying to do whatever they can, there would be no standards for employment and the basis for strikes would not be there. Works Cited http://www.cupe1975.ca/bursary/burs4.html http://canadaonline.about.com/od/canadianhistory/a/winnipegstrike.htm How to cite Winnipeg General Strike, Essay examples

Paula Moderzon

Paula Moderzon-Becker Biography Paula Moderzon-Becker was an outstanding German painter, representative of modernism, a pioneer of expressionism and the first artist in the world to which the museum in Bremen was dedicated. Outline1 Biography2 Key Ideas in Painting3 Famous paintings made by Paula Modersohn-Becker3.1 Elizabeth with Hens under an Apple Tree3.2 Landscape with Birch trunks3.3 Male nude standing Biography Paula Moderzon-Becker was born on February 8, 1876, in Dresden. Paula grew up in the family of engineer Voldemar Becker. Up to 12 years, Paula lived in a suburb of Dresden. The family moved to Bremen in 1888. Paulas mother introduced her daughter to the artists there. She worked in her own workshop. Parents who encouraged the aspiration of their daughter sent her to England in 1892. In addition to painting, the young artist studied English. On the advice of her father, in 1893, she entered the courses of teachers. Therefore, she was allowed to take private lessons in painting in the workshop of Bernhard Wiegandt. Paula began to paint portraits of her relatives and friends. Since women did not have the right to study at the Academy of Fine Arts, in 1896 Paula moved to Berlin and studied for six months at an art school under the Union of Berlin Artists. In order to receive painting lessons, it was necessary to have good skills in drawings. Paula worked hard before in 1897 she got permission to paint with the artist Jeanne Brown. In 1900 she visited Paris. She attended Paris Academy of Colarossa on the drawing of a nude. May 25, 1901, Paula Becker married Otto Moderzon. In 1903, Paula returned to Worpsved. But soon again she went to Paris. She offered her husband to go with her, but Moderzon denied French art. On her return to Worpsved, Paula studies the work of Paul Gauguin. And very soon she left for Paris again. In February 1906 Paula Moderzon-Becker left her husband. In Paris, Paula had her own small workshop. In September 1906, Otto Moderson came to Paris to support Paulo. A year later they return to Worpsved. Paula was expecting a child, and it bore her. She could not paint pictures as often as before. Paula Moderzon-Becker gave birth to a daughter. Childbirth went through with complications. She died on 20 November 1907, when she was 31 years old. Key Ideas in Painting While living in Worpsved, her favorite theme was the melancholy-severe charm of swampy and meadow landscapes in the north of Germany. In 1903, when she went to Paris, she was interested in Japanese color wood engraving, painting still lives with simple geometric forms and images of people. She refused to accurately reproduce the details of objects and figures. Acquaintance with the paintings of Pablo Picasso simplified the bodily forms in her works. The desire to have her own child was reflected in her artwork as well. Paula writes portraits of babies. Famous paintings made by Paula Modersohn-Becker Among famous Paula’s artworks are Girl with Child, Portrait of Rainer Maria Rilke, Peasant Child with Pink Apron, Infant with her ​​mothers hand, Still Life with Pumpkin  and other. Elizabeth with Hens under an Apple Tree Painted in 1902 this work is now in the private collection. We can see here that the girl is not clear, as the painter  didn’t want to show the details of objects accurately. Landscape with Birch trunks This expressionistic landscape dates back to 1901 when Paula was in Worpsved. Male nude standing Nude painting made with coal in 1899. At that period Paula had a series of nude paintings and in 1900 she Paris Academy of Colarossa.

SPEAK Essays - Fiction, Literature, Films, Speak, Melinda Sordino

SPEAK by Laurie Halse Anderson ANTICIPATION GUIDE Before reading Speak, read and respond to the statements below. Think about each statement carefully before writing agree, disagree, or unsure in the Before column. When we finish reading Speak, we will revisit these statements and you will write agree, disagree, or unsure in the After column. |Before |Statements |After | | |1. The pressures of fitting in at high school are greater | | | |than any other point in one's life. | | | |2. Students who are depressed are simply afraid to deal with| | | |their real or perceived problems. | | | |3. There is a difference between being quiet and being | | | |withdrawn. | | | |4. Students should not tell teachers about their personal | | | |problems, no matter how serious. | | | |5. A girl who dresses provocatively deserves any negative | | | |attention she gets. | | | |6. Girls are more likely than guys to say they have been | | | |sexually harassed. | | | |7. Whatever happens at a party should stay at the party. | | | |8. If someone is drunk or high, she or he is not responsible| | | |for her or his actions. | | | |9. Parents simply don't understand the problems teenagers go| | | |through. | | | |10. People who are quiet have something to hide. | | Compare your Before column to your After column. Have any of your opinions changed? If so, which ones and what made you change your opinion? If not, why do you think your opinions stayed the same? Book Structure: No numbered chapters. Four Marking Periods: First Marking Period - pages 2-46 Second Marking Period - pages 47-92 Third Marking Period - pages 93-137 Fourth Marking Period - pages 138-198 Plot Overview: Melinda Sordino is a freshman in high school (grade 9). She attended an end-of-summer party where she experienced a traumatic event, and called the cops. The cops busted the party, so everyone is mad at Melinda. Her old friends won't talk to her, and people who only know of her think she is a snitch. No one knows the real reason Melinda called the police. Melinda now has no friends and is not close to her parents - she feels completely alone. She starts skipping school and speaking very little. She is basically mute, except when she absolutely has to speak. Speak is about how Melinda struggles through her first year of high school and how she learns to cope with what has happened to her. Themes: Adolescence Growth Communication Depression Point of View: First person narrator from Melinda's perspective Characters: Protagonist: Melinda Sordino Antagonist: Andy Evans Setting: Place: Merryweather High School in Syracuse, New York Time: occurs over the course of a full school year Conflicts: Character versus Character(s) Character versus Self Character versus Circumstances Character versus Society First Marking Period Questions: 1. If something is ironic it is happening in a way that is opposite to what is expected. Think about how Melinda (and perhaps many other students) think about high school. Why do you think the name Merryweather High might be an ironic name for a high school? 2. On page 4, Melinda lists the groups (cliques) at Merryweather High school. Each group has its own special interests and characteristics that are different from the other groups. Why do you think members of different social groups often insult each other? 3. After she lists the social groups of Merryweather High, Melinda puts herself in a category she calls "Outcast." What does it mean to be an outcast? Look up the meaning in a dictionary, or infer the meaning from the text. 4. Think about how Melinda feels in Art class. Why is Mr. Freeman an appropriate name for the Art teacher? 5. On pages 5 and 6, Melinda list the "First ten lies they tell you in high school." Write out one lie you agree with and one lie you disagree with. Explain why you agree or disagree with each lie. 6. Is Heather a good friend for Melinda? Explain why you think she is or isn't. First Marking Period Journal Response Write a journal response about your reaction to the first section of Speak. You may use one of the prompts provided, or you may choose to write about something else that moved you. Try to fill all of the lines with your thoughts. Prompts: . Think back to your

Acid-Base Indicator Definition and Examples

Acids In chemistry and cooking, many substances dissolve in water to make it either acidic or basic/alkaline. A basic solution has a pH greater than 7, while an acidic solution has a pH less than 7. Aqueous solutions with a pH of 7 are considered to be neutral. Acid-base indicators are substances used to determine roughly where a solution falls on the pH scale. Acid-Base Indicator  Definition An acid-base indicator is either a weak acid or weak base that exhibits a color change as the concentration of hydrogen (H) or hydroxide (OH-) ions changes in an aqueous solution. Acid-base indicators are most often used in a titration to identify the endpoint of an acid-base reaction. They are also used to gauge pH values and for interesting color-change science demonstrations. Also Known As: pH indicator Acids Perhaps the best known pH indicator is litmus.  Thymol Blue, Phenol Red and Methyl Orange are all common acid-base indicators. Red cabbage can also be used as an acid-base indicator. How an Acid-Base Indicator Works If the indicator is a weak acid, the acid and its conjugate base are different colors. If the indicator is a weak base, the base and its conjugate acid display different colors. For a weak acid indicator with the genera formula HIn, equilibrium is reached in the solution according to the chemical equation: HIn(aq) H2O(l) ↔ In-(aq) H3O(aq) HIn(aq) is the acid, which is a different color from the base In-(aq). When the pH is low, the concentration of the hydronium ion H3O is high and equilibrium is toward the left, producing the color A. At high pH, the concentration of H3O is low, so equilibrium tends toward the right side of the equation and color B is displayed. An example of a weak acid indicator is phenolphthalein, which is colorless as a weak acid, but dissociates in water to form a magenta or red-purple anion. In an acidic solution, equilibrium is to the left, so the solution is colorless (too little magenta anion to be visible), but as pH increases, the equilibrium shifts to the right and the magenta color is visible. The equilibrium constant for the reaction may be determined using the equation: KIn [H3O][In-] / [HIn] where KIn is the indicator dissociation constant. The color change occurs at the point where the concentration of the acid and anion base are equal: [HIn] [In-] which is the point where half of the indicator is in acid form and the other half is its conjugate base. Universal Indicator Definition A particular type of acid-base indicator is a universal indicator, which is a mixture of multiple indicators that gradually changes color over a wide pH range. The indicators are chosen so mixing a few drops with a solution will produce a color that can be associated with an approximate pH value. Table of Common pH Indicators Several plants and household chemicals can be used as pH indicators, but in a lab setting, these are the most common chemicals used as indicators: Indicator Acid Color Base Color pH Range pKIn thymol blue (first change) red yellow 1.2 - 2.8 1.5 methyl orange red yellow 3.2 - 4.4 3.7 bromocresol green yellow blue 3.8 - 5.4 4.7 methyl red yellow red 4.8 - 6.0 5.1 bromothymol blue yellow blue 6.0 - 7.6 7.0 phenol red yellow red 6.8- 8.4 7.9 thymol blue (second change) yellow blue 8.0 - 9.6 8.9 phenolphthalein colorless magenta 8.2 -10.0 9.4 The acid and base colors are relative. Also note some popular indicators display more than one color change as the weak acid or weak base dissociates more than once. Acid-Base Indicators Key Takeaways Acid-base indicators are chemicals used to determine whether an aqueous solution is acidic, neutral, or alkaline. Because acidity and alkalinity relate to pH, they may also be known as pH indicators.Examples of acid-base indicators include litmus paper, phenolphthalein, and red cabbage juice.An acid-base indicator is a weak acid or weak base that dissociates in water to yield the weak acid and its conjugate base or else the weak base and its conjugate acid. The species and its conjugate have different colors.The point at which an indicator changes colors is different for each chemical. There is a pH range over which the indicator is useful. So, the indicator that might be good for one solution might be a poor choice to test another solution.Some indicators cant actually identify acids or bases, but can only tell you the approximate pH of an acid or a base. For example, methyl orange only works at an acidic pH. It would be the same color above a certain pH (acidic) and also at neutral and alkaline values.

Annotated Biography Essays - Sport Club Do Recife, Sport

Annotated Biography Dayton, Kels. "Ask a Coach: Should I Specialize in One Sport in High School?"SportzEdge. News 8, 16 Sept. 2013. Web. 27 Dec. 2015. http://sportzedge.com/2013/09/16/ask-a-coach-should-i-specialize-in-one-sport-in-high-school-2/>. I used this article to support my claim that playing more than one sport in high school is good for athletes. You get a firsthand look at what college coaches look for from an actual college coach who knows about recruiting and has been doing so for 20 plus years. You also get examples of great athletes who played multiple sports in high school who are sports super stars such as LeBronJames Fakehany, Tom. "ONE-SPORT HIGH SCHOOL ATHLETES."1 Sport Athletes. 18 Dec. 1995. Web. 27 Dec. 2015. http://home.earthlink.net/tfakehany/1sport.html>. This article counters my claim that playing multiple sports is beneficial. The article states that even though schools support playing multiple sports focusing on one main sport is the best way to get recruited forthatsport.Frollo, Joe. "Playing Multiple Sports Builds Better Athletes." Playing Multiple Sports Builds Better Athletes. 24 Oct. 2014. Web. 27 Dec. 2015. http://usafootball.com/blogs/health-and-safety/post/8942/playing-multiple-sports-builds-better-athletes>. This article supports my claim that playing multiple sports will benefit more than hurt athletes in the long run. In the article there are examples of how playing multiple sports can help them develop duplicate skills to help them a better all-around athlete. "One Sport Athletes."High School Sports Stuff. 20 Jan. 2015. Web. 27 Dec. 2015. http://highschoolsportsstuff.areavoices.com/2015/01/20/one-sport-athletes/>. This article supports my claim that playing multiple sports is good.thearticle includes great points about skills picked from different sports that can be used in another sport. It also includes points about athletes who are not looking to be recruited, but who play for the fun of playing. Oz, M.D., Mehmet, and Michael Roizen, M.D. "Kids Should Play More Than One Sport."Newsmax. 8 Oct. 2014. Web. 27 Dec. 2015. http://www.newsmax.com/health/Dr-Oz/oz-dr-sports-children/2014/10/08/id/599330/>. This article supports my claim that playing multiple sports is good. The article includes facts from doctors about over repetitiveness from playing just one sport is a very high risk for injury. Satterfield,Lem. "Coaches Recognize Competitiveness in Players Who Play Multiple Sports."ESPN. ESPN Internet Ventures, 4 Oct. 2011. Web. 27 Dec.2015. http://espn.go.com/high-school/lacrosse/recruiting-road/story/_/id/7057666/coaches-recognize-competitiveness-players-play-multiple-sports>. This article supports my claim that playing multiple is very beneficial for athletes. In this article collegecoaches give their reasons for wanting to recruit multiple sport athletes because of their competitiveness. Wippel, Teresa. "Should Your Child Play Just One Sport?"-ParentMap. 1 Mar. 2007. Web. 27 Dec. 2015. https://www.parentmap.com/article/should-your-child-play-just-one-sport>. This depicts my claim that playing more than one sport is beneficial. The article includes points about the pressure being too much for kids to handle with doing more than one sport.

Human resource strategy Essay Example | Topics and Well Written Essays - 2500 words

Human resource strategy - Essay Example Based on the new developments in the business world, HRM strategies are also undergoing drastic changes at present. Earlier, HRM functions were labeled as personnel management. Later, it acquired the form of human resource management. Now instead of HRM, Strategic human resource management (SHRM) is gaining grounds in organizations of the modern world. The core of SHRM is to prepare the employees in accordance with the strategies of the organization. The integration of the employees in to the main streams of organizational activities is a modern day business strategy. Along with the expansion of human resource management or strategic human resource management, lots of ethical problems are also arising. When organizations move into foreign markets, they must adapt to communication, culture and human resource issues. Domestic business and international businesses have more differences than similarities. Moreover, ethical dimensions of HRM would be more significant in cross cultural bus inesses than in domestic businesses because of the huge differences in cultures between countries. â€Å"Education, social standing, religion, personality, belief structure, past experience, affection shown in the home, and a myriad of other factors will affect human behaviour and culture† (Encina, 2007). Most of the current organizations have extremely diverse workforce and hence the interests of these diverse workforce may often been clash each other. Strategic HRM policies should be formulated in such a way that all the employees working in an organization get equal opportunities and fair treatments. â€Å"Ethical conventions should be fully addressed by the HRM profession and ethics be integrated into the strategic HRM process† (Carey, 2011) Business ethics was not much interested in the issues relating to the ethical management of employees till recent times. â€Å"Apart from the development of ethical awareness among managers and the ethical dimension of change management processes, there has been little debate around the ethical basis of much HR policy and practice† (Winstanley & Woodall, 2000, p.1). However, current business Gurus are aware of the necessities of managing employees in an ethical way for the sustainment of their business. This paper briefly analyses the ethical dimensions of strategic HRM in future Ethical dimensions of strategic HRM in future The work culture in different countries are different and hence while employing diverse workforce, an organization may face clashes between the interests of diverse employees. For example, Americans like to work under a stress free environment because of the immense freedom they are enjoying in their country because of democracy. However, Chinese may not enjoy such freedom in the work places of their country because of the tight communist administration. An American working in China may face extreme difficult situations in China because of the contrasting business management ph ilosophies he may face in China. Strategic HRM should give more focus in such areas in order to reduce the stress levels of the diverse employees. â€Å"There is a powerful argument that the wider economic system and ultimately the business organisations within it exist to serve human and societal needs rather than the opposite†

Discuss the Greek background into which Christianity developed during Essay

Discuss the Greek background into which Christianity developed during the first century A.D.and discuss the Jewish bckground into which Christianity was born uring the first century A.D - Essay Example ace, the order would have to overcome the culturally and religiously embedded polytheistic ideas that served as a bridge between the current Greek society and the historical Greek society. Making the cultural transition from this set of religious doctrine to that of the Christian one would not be seamless; however, there were aspects of the Greek religious and cultural landscape that facilitated the shift in parallel to one taking place in the Roman Empire. The Greek religious context of First Century Christianity was predominantly one of an ideologically opposed polytheism in which a pantheon of different gods and goddesses took part in influencing the course of human and natural events. The hierarchy of gods, with a king Zeus having a level of power over other gods, displays a very anthropomorphic center in the Greek folk religion. Each of these gods and goddesses possessed control over some general category of nature, or, in other cases, some abstract concepts. The Greek deities were immortal but not all-powerful (omnipotent). The gods were subject to a sense of fate that could not be violated. Like human beings, the Greek deities were not perfect, and often had extensive relationships with human beings. The gods had human vices and fell victim to the same kinds of weaknesses in will that humans are famous for, such as the will to outdo others in competition. In addition, the Greeks associated certain individual gods with cities, su ch as the famous association of Athena with the city of Athens. Clearly, there are some ideological parallels between this description of Ancient Greek faith and the orthodox Christianity that emerged in the First Century. The Christian God was immortal (though omnipotent), and was profoundly anthropomorphic, especially in the traditional Old Testament conception. The hierarchy of gods in the Greek religion corresponds to the hierarchy of the orthodox faith, especially in what many Christians would come to create with the Great

Report on Consumer Behavior of Soft Drinks Essay Example for Free

Report on Consumer Behavior of Soft Drinks Essay Need for the study With the economic liberalization in India a number of global companies have been coming forward to invest in India and tapping perhaps and worlds biggest growing market. As the floodgates have been opened up for Multinational Companies, the global giant Coca-cola also decided to make an entry into the Indian market. In India, the per capita consumption of soft drinks is at rock bottom level even less than our neighboring countries Pakistan and Bangladesh, where it is four times as much. The last summer was particularly sweltering one, with temperatures hitting the high 40s in some places yet; bottles were disappearing from shelves faster than they could be replaced. In the peak season, they found themselves short of capacity and having to turn around their trucks faster and faster to slake the greater Indian thirst. With growth rates zooming into the double digits, bottlers have been propelled into expanding capacities. With their big-time plans, the multinationals have changed the face of this business, long dominated by small-time businessmen. If demand continues to increase annually at an average of 20 percent, then volumes could reach one billion cases within ten years. 4 These arc ambitious targets and to reach them the cola makers will have to build capacity, infrastructure, make their bottlers more available and more affordable. There are 5. 00,000 retailers stocking soft drinks in India. Also, soft drinks which retail at any where between Rs. 9. 00 and Rs. 12. 00 are expensive when measured against purchasing power. As they concoct their strategies, keeping an eye on each other all the time, ultimately theres only one guy they have to watch out for, who will determine their fortunes: the consumer. The real race to quench his thirst has just begun 5 Objectives of the studyTo study about the consumer preference with regard to soft drink To study about the consumer perception with regard Coca — Cola To understand the Promotional Strategies To find out the medium which is most effective in reaching the consumers? 6 Research methodology Data will be collected from a sample size 1000 and distributed over different areas by using simple Random Sampling. Random Sampling consists of 1. Demographic Segmentation 2. Sociocultural Segmentation 3. Use-Related Segmentation 4. Use-Situation Segmentation Analysis 1. Data Analysis is done both qualitatively and quantitatively. 2. The analysis is presented pictographically using bar graphs The period of the study is past one year 7 Scope of the study The new economic policies of the Govt. of India adopted in the mid eighties were given further impetus by the early nineties. The Indian market has undergone considerable changed as a direct consequence of many of these policies and soft drink industry is no exception to this. Keeping the above mentioned perspective in the background, the researcher has selected soft drink market, since the marketing task his became more challenging and intensive competition has opened up new vistas. Companies are evolving marketing strategies by studying the demands of the market place increasingly penetrating into appropriate market segments introducing differentiated products to improve their market share. The soft drink market has achieved an accelerated growth in the past decade. Soft drinks include ail types of non alcohol carbonated flavored or otherwise sweetened beverages. The entry of Pepsi and the reentry of Coca Cola in the India market arc inevitably facing stiff competition but the ultimate winner is customer/consumer. This has led the researcher to study me perception of consumers towards different brands of soft drinks and to gauge out the 8 promotional strategic being adopted by the marketers to lure promiscuous buyers and win a larger share in the markets.

Promotion of Education in Africa Essay -- basic education, literacy, so

Topic 1: Promotion of Education in Africa The issue of basic education in the world, especially in Africa has been in the spotlight, waiting impatiently to be solved. The UN, with its Millennium Development Goals, has cited education as one of its top priorities to be achieved by 2015. The African Union, with its Second Decade of Education, has emphasized the need for primary education in Africa to ensure gender equality and the enhancement of African cultural values. Sadly, in many African nations, especially those in Sub-Saharan Africa, adult literacy rates are well below 50%, and many youth lack the most basic and primal educational opportunities. The delegation of South Africa recognizes this urgent need of promotion of education in Africa. Background As a fortunate nation, South Africa has a stable educational infrastructure and a sound â€Å"baseline† for elementary education. In South Africa, the average adult literacy rate is a good 93 percent, as compared to the international average of 84 percent (2010) and the staggering 62 percent of Africa. To continue, most youth has completed grade 9, which concludes their general education and ends their compulsory schooling. And to breathe a sigh of relief, there is little gender disparity in the South African education system. However, there are always some holes. Despite the solid literacy rate- this is defined as a person 15 years or older and can write a short statement about his or her life- South Africa lacks strong secondary and tertiary education. As stated from a study conducted by the OCED (Organization for Economic Co-Operation and Development), â€Å"some three-quarters of South African adults have completed at least grade 6, half has completed grade 9, and just under one-thir... ...amic Militant Organizations in Africa "Africa's Militant Islamist Groups." BBC News. BBC, 5 Dec. 2013. Web. 18 Apr. 2014. . Nkala, Oscar. "Little Terror Threat in South Africa – Report." Home. Defence Web, 5 June 2013. Web. 18 Apr. 2014. . "South Africa: Consolidated Acts." Protection of Constitutional Democracy against Terrorist and Related Activities Act 2004. South African Legal Information Institute, n.d. Web. 18 Apr. 2014. . The War on Terrorism in Africa. N.p.: Westview Press, n.d. PDF. http://www.cfr.org/content/thinktank/Lyman_chapter_Terrorism.pdf

A World Lit Only by Fire

A World Lit Only By Fire, a magnificent book written by William Manchester transform the way people saw the medieval and the renaissance times. He portraits a very vivid image of that time opening our eyes to what really happen to the people who lived that era. The book is divided into three parts: The Medieval Mind, The Shattering and the last part, One Man Alone. The first part of the book introduce us to a new perspective and understanding of what the author believe, thanks to his investigations, form and mold the medieval mind.The society of this time was one of indifference toward others, corruption, violence, and cruelty. Men of the church were blind by the power the Holy See gave them, and by the name of that same church, the one that was supposed to protect the interest of all the faithful Christian, was the one that cause thousands of innocent deaths. When you read things like this you think that it can’t get worse, but when you keep reading you realize that not even the sins where taken seriously and that corruption was worse than we thought but, the worst part of the situation were the diseases.Education was so ignored by the people that at some point as the people infected with the diseases try to reach for a doctor or a person that can cure them they find themselves without a good treatment just because the ignorance led them to became an illiterate society with a seriously lack of ethics, moral but more important, the base of success, the education.At the end of this part Manchester set very clearly that this society was so insignificant, they were like stock in time, fighting the impossible, the change, a revolution toward a new time fill with amazing thinkers and discoveries but with the same or worse characteristic that define this era, corruption and injustice. This new beginning is the Renaissance. With the re birth of an era the author begins the second part of the book The Shattering.Manchester goes more deeply in the corruption of t he church and the new intellectuals that emerged to expose to the world their ideas of what in their perspective was for example the way to obtain salvation. For example we have Erasmus and Martin Luther, two extraordinary humanists that fought basically against â€Å"The Invincible† the Catholic Church. Both of them spread their ideas of salvation and faith but at the same time they reveal the mistakes and corruption committed by church officials.The Church of that time was sick with the power it have. Especially, the one sick with this power was the head master, The Pope. He was the first to commit mortal sins like murders and incest. Thanks to all the corruption and indifference from the church, the faith of the fellows toward them began to decrease rapidly causing the church to lose a lot of the power they loved so much. The renaissance was an era of change, fighting, and unexpected discoveries made by extraordinary people.This lead us to the final part of the book, One M an Alone, basically concentrated in the trajectory, discoveries, and life of Ferdinand Magellan. He and his voyages will change completely and irrevocably the world as they know it. William Manchester as hi let us know in the note at the beginning of the book almost all of his sources are secondary. Most of these sources are documents and studies about the medieval and renaissance time, but he also uses some primary sources like Life on a Medieval Barony by William Stearns Davis.He pictures the medieval community and experiences very clearly. Another source Manchester uses is works from Dr. Timothy Joyner and James Boyden, both work help the author complete this book with real facts from historians who studied very deeply the medieval and renaissance era. In my honest opinion this is not the type of reading I actually expect to be reading in school. I was expecting something more monotonous, but never expect to find this reading so interesting.Maybe is the fact that most of the them es treated in the book are not new to me. Being this my first time reading from William Manchester I can really say I love his works but I can really tell that if all his books are like this one I will certainly enjoy them. A World Lit Only By Fire has opened the eyes of every single person that read it to the reality of that time it actually make me feel like I was living in that monstrous time but it was a really great experience.However this book is not for everybody the people how read it have to be open mind to the past and most important they have to know how interpret the point of view and critics of the author. Finally William Manchester is a great writer; he knows how to balance between his critics, point of view, and the reality of the facts. Reading this brightening book was worth my summer time and I hope that the books I will be assigned to read in the future are as good as this one.

Tolerance and World Peace

Tolerance and World Peace What is the meaning of tolerance or world peace? Tolerance is the ability to the fundamental of other cultures without using individuals or own culture to compare others. World peace is the freedom, peace, and happiness between all nations and people. The two articles, â€Å"Patriotism and Cosmopolitanism† by Martha Nussbaum and â€Å"Don’t Forget the Little Plattons† by Michael McConnel, explains the tolerance and cultures. In my own understanding from the 2 articles, I think patriotism is opposite from the tolerance.However, the more patriotic the citizen is towards their own country, they will become less tolerant of other cultures. Nussbaum argues that all citizens should act cosmopolitanism to be sure there are truth, peace and justice in the world. Everyone should be able to â€Å"come together as a single body†1 (Nussbaum 1996, 10) to unite with other fellow human beings and not categorize each other into groups. This will lead to an increase of world peace. There is a quote when Nussbaum agree with this, â€Å"It is this community that is, fundamentally, the source of our moral obligations.With respect to the most basic moral values, such as justice, ‘We should regard all human beings as our fellow citizens and neighbors’. We should regard our deliberations as, first and foremost, deliberations about human problems of people in particular concrete situations, not problems growing out of a national identity that is altogether unlike that of others. â€Å" 2 (Nussbaum 1996, 7) This quote is referring to when the human that are living in the world today should observe being as a citizen for their country and neighbours within their community.When the citizen is devoting himself to the nation, it is most likely for the person to be more ignorant of the values and rights to be followed around the world. This is why there is no world peace because citizen would rather to focus on his or her own values and rights. There are other options for students as an advantage to be learning about other cultures and beliefs. â€Å"As students here grow up, is it sufficient for them to learn that they are above all citizens of the United States but that they ought to respect the basic human rights of citizens of India, Bolivia, Nigeria and Norway†¦Ã¢â‚¬  3 (Nussbaum 1996, 6)To bring changes to the tolerance level of nationalities is the students to be taught that they are the citizens of the world, not the citizen of their country. If the teachers in school taught the students more about other cultures from different countries this will build more tolerance education in the students. They would have better understanding of their beliefs and cultures and also others too. This will benefit a difference within the nationalities about tolerance.There are three arguments for the second concept of education from the Stoics that Nussbaum explain about tolerance and a bit of world p eace. Firstly, â€Å"they hold that they study of humanity as it is realized in the whole world is valuable for self-knowledge: we see ourselves more clearly when we see our ways in relation to those of other reasonable people. †4 (Nussbaum 1996, 8) I agree with him because we are here in this world for a reason, we are here to learn about the world as one society, world peace.World peace will make it easier for people to relate to others to expand more self-knowledge like self-actualization. Secondly, â€Å"†¦that we will be better table to solve our problems if we face them in this way. †5 (Nussbaum 1996, 8) This is true because looking in the past of the history from different politics has been cause from assassinations and wars. The best example is Hilter and his Nazi army when they try to take over Europe by killing people that are different such as being black, disable, Jews and more. We try to avoid these dangers by decreasing large groups in the world comm unity.Finally, they talk about that â€Å"†¦stance of the kosmou polites is intrinsically valuable, for it recognizes in people what is especially fundamental about them, most worthy of respect and acknowledgement†¦Ã¢â‚¬  6 (Nussbaum 1996, 8) If the world is seen as one society or entity, citizen will be tolerance about their cultural difference. They will focus more on what they would have in common. â€Å"These qualities may be less colourful than local or national traditions and identities†¦Ã¢â‚¬  7 (Nussbaum 1996, 8) We as individual still keep our culture, traditions, religion, and ethnicity even though the world is going to unite as one society.Even though the world comes together as world peace, it does not represent that we will not be able to undefined ourselves of whom we are. The point of this is to not separate each citizen from our community we are part of. But, we should hold the humanity that is part of it. This is how we should visualize ourselves as, â€Å"Our task as citizens of the world will be to draw the circles somehow toward the center. Making all human beings more like our fellow city-dwellers, and so on. We need to give up our special affections and identifications, whether ethnic or gender-based or religious.We need not think of them as superficial, and we may think for our identity as constituted partly by them. † 8 (Nussbaum 1996, 9) When I read Nussbaum’s article, I thought ‘ Isn’t Nussbaum being to self-centered? ’ But when I over read it again I understood her arguments and points she was pointing out relating to tolerance. On the other hand, McConnell’s article had also suitable points he wanted to argue about. With McConnell’s point, I agree to what he is explaining about tolerance that it does not come from the educational wise but it comes from home whereas family and older generation explain their own culture.Most of my point of view of different culture or belief did come from teaching in school when I took a World Religion course in grade 10. I learn a lot more about other beliefs and cultures more than usual. It was interesting because most culture have their own traditions that are practically the same traditions than other cultures. I also learn the ideas from my family and realtives. I do believe that the students should learn and understand the cultural teachings in school, so that they have a strong influence that could possibly change their perceptions. They key to moral education is to fuse the sentiments (especially love) to teaching of the good. We begin to do good because we love our preceptors (especially our parents); we want to please them and we want to be like them. We continue to do good because that is the kind of person we have grown up to be. † 9 (McConnel1996, 79) McConnell is trying to say in this quote is that tolerance start at home and than become more involving with the community. He also said that one could be part of the local community even though cosmopolitanism states that.But, it cannot be forgotten that the main purpose is to look at the world as a one society, world peace. Things will have to be accepted in some days where as it is possible that the communities maybe forgotten. To the conclusion, the 2 articles â€Å"Patriotism and Cosmopolitanism† by Martha Nussbaum and â€Å"Don’t Forget the Little Plattons† by Michael McConnel, had made excellent point of view of their own opinion about tolerance and cultures. I agree more of Nussbaum side because he stated that the world would be a better place if we all became more tolerant of other beliefs.This will help the world to have peace and as one culture. A way to change this is to change the teaching in school, whereas students can learn more about other cultures. However, the students’ opinions will change with the influence when the parent or relative tell the stories about their own culture. Another argument is the Stoics when the world was to get ride of smaller political groups that the war of dangers would be reduced. Both sides of these two arguments had made perfect sense points about the author’s opinion about tolerance and world peace.It is hard to select which to select as the best points, but in my opinion I liked Nassbaum points because she explained the benefits. On the other hand, McConnell explained the potentials. Nassbaum leaves me with better agreement on his article. Notes 1. Martha Nussbaum et al. , â€Å"Patriotism and Cosmopolitanism,† in For Love of Country: Debating the limits of patriotism, ed. Joshua Cohen (Boston: Beacon Press, 1996), 10. 2. Nussbaum, 7. 3. Nussbaum, 6. 4. Nussbaum, 8. 5. Nussbaum, 8. 6. Nussbaum, 8. 7. Nussbaum, 8. 8. Nussbaum, 9. 9.Micheal McConnell et al. , â€Å"Don’t Forget the Little Platoons,† in For Love of Country: Debating the limits of patriotism, ed. Joshua Cohen (Boston: Beacon Press, 199 6), 79. Works Cited McConnell, Michael. et al. â€Å"Don’t Forget the Little Platoons. † In For Love of Country: Debating the limits of patriotism, edited by Joshua Cohen, 78-84. Boston: Beacon Press, 1996. Nussbaum, Martha, et al. â€Å"Patriotism and Cosmopolitanism. † In For Love of Country: Debating the limits of patriotism, edited by Joshua Cohen, 2-17. Boston: Beacon Press, 1996.

Law of Multiple Alleles

Law of Multiple Alleles Multiple alleles is a type of non-Mendelian inheritance pattern that involves more than just the typical two alleles that usually code for a certain characteristic in a species. With multiple alleles, that means there are more than two phenotypes available depending on the dominant or recessive alleles that are available in the trait and the dominance pattern the individual alleles follow when combined together. Gregor Mendel only studied traits in his pea plants that showed simple or complete dominance and had only two alleles that could contribute to any one trait the plant showed. It wasnt until later that it was discovered that some traits can have more than two alleles that code for their phenotypes. This allowed many more phenotypes to be visible for any given trait while still following Mendels Laws of Inheritance. Most of the time, when multiple alleles come into play for a trait, there is a mix of types of dominance patterns that occur. Sometimes, one of the alleles is completely recessive to the others and will be masked by any of those that are dominant to it. Other alleles may be co-dominant together and show their traits equally in the phenotype of the individual. There are also some cases where some alleles exhibit incomplete dominance when put together in the genotype. An individual with this type of inheritance connected to its multiple alleles will show a blended phenotype that mixes both of the alleles traits together. Examples of Multiple Alleles The human ABO blood type is a good example of multiple alleles. Humans can have red blood cells that are of type A (IA), type B (IB), or type O (i). These three different alleles can be combined in different ways following Mendels Laws of Inheritance. The resulting genotypes make either type A, type B, type AB, or type O blood. Type A blood is a combination of either two A alleles (IA IA) or one A allele and one O allele (IAi). Similarly, type B blood is coded for by either two B alleles (IB IB) or one B allele and one O allele (IBi). Type O blood can only be obtained with two recessive O alleles (ii). These are all examples of simple or complete dominance. Type AB blood is an example of co-dominance. The A allele and the B allele are equal in their dominance and will be expressed equally if they are paired together into the genotype IA IB. Neither the A allele or the B allele is dominant over each other, so each type is expressed equally in the phenotype giving the human an AB blood type.

Dug Legalization in America Essay Example | Topics and Well Written Essays - 1250 words

Dug Legalization in America - Essay Example Users who cause no harm to others are incarcerated which not only ruins their professional and private lives but overcrowds the prison system which allows the early release of violent criminals. It has been said that trying to stop drugs is like trying to stop the rain, still, the ‘war’ continues as a prominent issue. Over half of the prisoners in jail are there for drug ‘crimes.’ This causes overcrowding which results in the early release of dangerous, violent criminals. It is illogical from a societal view and inhumane to individuals who are marked as a criminal for life for activity that causes no harm to others. Those who are addicted receive little or no therapeutic help in prison. Instead of imprisoning people that need help, rehabilitation programs are a much more effective method to treat the problem but a rehabilitation system will not succeed if drugs continue to be illegal.   Drug abusers will hardly seek help from the same government that tosses them in jail for the same thing. The hypocrisy of the drug war is apparent. All illegal drugs combined account for about 4,500 deaths in this country per year while tobacco is responsible for the deaths of 400,000 people annually and alcohol ends 80,000 people’s lives every year. (Fu, 2006) Legislators will not ban smoking because they indicate regulation regarding what adults do in privacy including what they can put into their bodies is clearly unconstitutional and an infringement on personal liberties.   Everyone can differentiate the distinction between a person that takes in an occasional alcoholic beverage and one who commits crimes while drunk.   Why can’t this simplistic reasoning be applied to drug users? Our code of law is founded upon a principle of presumptive rationality.   Rational adults should be allowed to make personal choices as long as those actions cause no harm to others.   The U.S. government is unequivocally unjustified in choosing this particular

Discuss the agency problem relating to multinational companies, and in Essay

Discuss the agency problem relating to multinational companies, and in particular multinational banks, and how, they differ from - Essay Example The situation of agency problem is such in many of the organizations that the agents or the management of the organization makes use of their authority for deriving personal benefits rather than benefits of the principals or the shareholders. In other words, agency problem arises due to the conflicting interests among the management, creditors and shareholders’ regarding the goals of the organization as well as that of the concerned parties (Investopedia, 2011). The agency problem in multinational companies can be appropriately discussed by focusing on the ways as to how the supervision and regulation affects the risk-taking measures of the banks in the host-country (Ongena & Et. Al., 2011). This research paper is aimed to present the discussion on agency problem in multinational companies, particularly banks, through review of various aspects related to the evolution of the problems. The research also aims to present a comparative study of the agency problems faced by the mul tinational organizations and domestic organizations. Two Most Common Agency Problems in Banks In the non-financial corporations, an incentive is provided to the shareholders through limited liability that allows them to seize bondholders’ wealth by increasing the level of risk. The government is indulged in protecting the bond holders from the outcome of risk taking activities of the banks. Thus, the shareholders’ incentive to supervise and restrain risk taking is low. In the banking literature, such situation of absence of discipline is known as the â€Å"moral hazard problem associated with deposit insurance†. A second very common situation of agency problem arises due to the limits on the wealth of managers that forces a separation of control and ownership. This forces the managers to consider their own objectives to be more important than that of the shareholders (Demsetz, 1997). Agency Problems and Risk Taking at Multinational Banks The root cause of agency problems in multinational companies, particularly banks is related to the structuring of regulations for multinational banking units. The host country is more interested in structuring the regulations in such a way that would provide disadvantage to the foreign firms to compete with the domestic firms. But this notion would result in inconsistency with the objective of a single market (Baum, 2002). The consequence of leaving the supervision and regulation in the home country, as evident from the case of the European Union, is that the member countries adopted different structures of regulation and supervision for the financial institutions. Thus, if the multinational banks are faced with similar regulatory issues, they would either split according to functions or would consolidate regulation into one agency. In that case, in certain situations the Central Bank will be involved, whereas in other cases, it would not. Hence, it is evident that considering these regulatory issues, the multinational banks would select policy trade-offs on the basis of their degrees of responsibilities and

Fit And Filling Facility For The Elderly Assignment

Fit And Filling Facility For The Elderly - Assignment Example The most notable features of the space around and within the park are that the pathways are paved using colored concrete blocks. The paving of the pathways and the common areas are done using different colors, and that choice was made for different reasons. First, the choice of white materials for the pathways was made to guarantee that hygiene levels would remain as high as possible. Secondly, the different colors for the pavements will help the aged suffering from dementia to recall their respective rooms, and their way to facilities like the health center, the shopping center, and common facility amenities. From the outside, towards the front side of the facility, there is a pathway heading to the suburban shopping mall which is located about 50 meters from the facility. At the shopping mall, there are many of the stores that an aged person would need to visit, including a bread shop, a Starbucks outlet, and a wellness center, which provides aerobics, physical fitness, and physiotherapy services. From the outside, a visitor can see the two-bedroom apartments of different sizes, ranging from 825 to 2000 square feet. At one extreme side of the facility, close to the fence, there is the health center, where the elderly living at the facility are rushed for urgent medical care (Secker et al., 2003). At different sections of the facility, the common open parks will have different plant species, in order to help the aged to remember their respective house and the entrance to their main hall.

The Treaty of Portsmouth, 1905 Case Study Example | Topics and Well Written Essays - 1000 words

The Treaty of Portsmouth, 1905 - Case Study Example This paper provides an evaluation of the conflict, negotiation of the treaty as well as an evaluation of the suppositions and empirical evidence as provided by the relevant readings and will offer analysis of underlying dynamics of conflict along with recommendations. The Russo-Japanese War prevailed between 1904 and 1905 and was the initial major military conflict of the 20th century, which developed from the imperial aspirations of Japanese and Russian empires particularly over the territories of Manchuria along with Korea (Woodhouse et al 1-10). The principal fronts of the confrontation were the southern part of Manchuria particularly the regions around Mukden and Liaodong peninsula as well as the sea adjacent to Korea and yellow sea. The Russian realm endeavored to obtain a warm water harbor located in the area of Pacific Ocean for purposes of the navy and commerce since Vladivostok could be used in summer seasons and was dormant on other seasons. Port Arthur on the other hand co uld be used throughout the year. Negotiations between the two ambitious foes had failed right from the conclusion of the initial Sino-Japanese conflict making war inevitable (Wandberge 23). Japan resorted to war in order to become overriding in Korea. Following the failure of talks, Japan attacked the Russians soldiers stationed at Port Arthur, a position located in Liaotung that had been granted to Russian by China via lease; this marked the beginning of the war (Butler 247). It was evident that owing to the fact that the Russians were not well managed, Japan triumphed in numerous battle fronts. The outcomes of the military campaigns were a huge global surprise in the sense that the victory of Japan was unexpected and shifted the power arrangement in East Asia. These outcomes brought Japan to the global stage as a major member of the world community. The course of negotiation at Portsmouth Peace accord has been recognized as a clear epitome of multi-track mediation. Records from th e process had indicated that citizen diplomacy was prevalent at Portsmouth- residents of the area inspired the negotiators to bring peace especially during a number of social events in instances when the process was failing. This has been cited as an important pillar in diplomacy. There are five strategies of negotiations that include contention, yielding, avoidance, problem solving and compromise (Zartman and Rasmussen 4). Contention involves the aspect of obsession with individual goals and less concern for the goals of the other party. Contention leads to confrontation, which involves threats, and restrictions along with hostility. Yielding is a situation where both parties are more concerned with the requirements of the other party and not their own, which creates a situation of pleasing each other and lessening the apprehensions. Avoidance signifies the absence of interest in both parties. Problem solving is a concern for each party’s goals that create an opportunity to generate a solution. Compromise being the ultimate in conciliation is an endeavor that is never arrived with enthusiasm (Dana 63-66). Experts of international relations have often concentrated on power relations among nations as an imperative dynamic in a broad category of state conduct, which comprises of creating alliance and tactical interactions along with negotiations programs. It is evident that that the power equation between Russia and Japan played a

Gene-ablation and other genetic technique

Gene-ablation and other genetic technique How has the use of gene-ablation and other genetic techniques in mice altered our approach to scientific problems in pharmacology and physiology? 280 pts (8-12 pages, 11pt Arial font, double spaced) A gene is a region of DNA that controls a discrete hereditary characteristic, usually corresponding to a single protein or RNA1. Most scientists are interested in determining how genes, and the proteins they encode, function in the intact organism. One of the most direct ways to find out what a gene does is to see what happens to the organism when that gene is missing. Because mutations can interrupt cellular processes, mutants often hold the key to understanding gene function. A well accepted strategy for evaluating gene function is to create and characterize a gene knockout mouse. Virtually any gene in the germ line can be mutated through gene targeting in totipotent embryonic stem (ES) cells or to use gene ablation technology to knock-out either a specific gene or a specific cell type in an intact animal2. Both of these methods offer almost unlimited possibilities for addressing questions concerning the molecular and cellular biology of development, the relationship between geneti cs and biological function, unraveling the causes of disease, and enhance pharmaceutical research. ES cells are a versatile source of cells for repair of damaged and defective tissues in the adult body2. Totipotent embryonic stem cells have been used in vitro to generated precursors for oligodendrocytes and astrocytes. Transplantation of these ES cells into a model mouse of human myelin disease allowed the precursors to interact with host neurons and efficiently myelinate axons in brain and spinal cord. Further investigation of this mechanism could lead to pharmacological, physiological and therapeutic treatments. ES cells also make possible the most precisely controlled forms of genetic modification, allowing animals to be created with virtually any desired alteration introduced into their genome2. One way to produce a transgenic (knockout) animal is through gene targeting in totipotent ES cells. By incorporating a null allele into one allele of murine ES cells, and injecting these cells into early mouse embryos, one can create chimeric mice (heterozygous for the knockout allele) containing tissues derived from both host cells and ES cells2. Mating the chimeric mice allows one to confirm that the null allele is incorporated into the germ line and can breed these heterozygous chimeric mice to homogeneity producing progeny that are homozygous knockout mice2. A knockout mouse generated to carry a mutating apolipoprotein E (apoE) gene through inactivation by gene targeting in embryonic stem cells can be used as a model for atherosclerosis. apoE is a constituent of very low density lipoprotein (VLDL) synthesized by the liver and of a subclass of high density lipoproteins (HDLs) involved in cholesterol transport among cells. In humans a variant form of apoE, has been found to be defective in binding to the LDL receptor that is associated with familial type III hyperlipoproteinemia, a disease characterized by elevated plasma cholesterol and premature coronary heart disease. apoE deficient mice develop severe hypercholesterolemia due to a delayed clearance of large atherogenic particles from the circulation. A study was done to analyze the genesis of atherosclerotic lesions, including the nature of the cells involved, the sequence of cellular events and the anatomic location of specific lesion types over time on mice fed a normal or a high fat diet. They found that the lesions were distributed thought the arterial tree and contained many features of the specialized, chronic, inflammatory-fibroproliferative response characteristic of atherosclerosis with age. This mouse model is used to better understand the physiological role of apoE in lipid metabolism, atherogenesis, and nerve injury. The model can also be used as a way to test new pharmacological drugs in pre-clinical trials to determine drug interaction, new therapeutics or to develop variations of current drugs to better meet the needs of the vast array of genetic variability seen in the human population today. Gene ablation involves the homologous genetic recombination of a gene in such a way that the gene has been made â€Å"null†. Genetic ablation is a genetic engineering technique used to suppress selectively the growth of a specified cell line or cell type in an animal rather than suppress the activity of an individual gene2. Analyzing the in vivo function of cells can be accomplished through specific cell ablation. Using genetic ablation to produce a knockout mouse involves the injection of one or more transgenes (usually a DNA segment bearing its own promoter) into the pronucleus of a fertilized mouse oocyte, which, after reimplantation into a foster mother, gives birth to a transgenic mouse bearing one of several hundred copies of the transgene3. These mice again can be bred to produce a homozygous colony. An overexpression Sod2 transgenic mouse was generated through the use of pronuclear injection of the Sod2 gene into fertilized eggs. These mice overexpressed superoxide dismutase which catalyzes the conversion of superoxide anion to hydrogen peroxide and oxygen. Superoxide anions are reactive oxygen species (ROS) generated in the respiratory chain as a byproduct of mitochondrial respiration. ROS cause oxidative damage to key mitochondrial components, such as protein, lipids and DNA. They are thought to lead to an overall decline in cellular function and ultimately determine the life span of an organism. Sod2 trangsenic mice have been used to test the effects of overexpressing MnSOD on mitochondrial function, levels of oxidative stress or damage and live span in mice. They found that a two fold increase of MnSOD throughout the life of the organism resulted in a slight decrease in oxidative damage and enhanced resistance against oxidative stress. Oxidative damage is also associated wit h arthritis, heart disease, gastrointestinal disorders, multiple sclerosis, cancer and neurological diseases. This model can be used to physiologically improve ones understanding of oxidative stress and to develop pharmaceutical agents that can enhance ones ability to decrease or protect against oxidative damage. Customized gene targeted animal models include constitutive knockouts or knock-ins, or conditional knockouts or knock-ins of known genes, a gene family, mutant genes or artificially created reporters and gene constructs. A constitutive knockout is a model that provides a broad overview of gene function, by the inactivation of the gene of interest at the genetic level, by random mutation or targeted insertion4. The advantage of using this model is that you get a total inactivation of the gene in any cell4. The disadvantage of this model is that the phenotypes can be complex since all organs are affected4. A conditional knockout is a model that provides a research model of high potential, by targeting tissue-specific inactivation of the gene of interest, through the use of recombinase4. Recombinase is an enzyme that deletes the DNA fragment located between the two recombinase-specific sites4. This tissue-specific expression of the recombinase allows the inactivation of the gene of inte rest only in the tissue were the recombinase is expressed4. There are two advantages to using this model, the first is the inactivation is restricted to specific tissues and the second is that several tissue-specific models can be made in parallel4. The disadvantages of using this model include the efficiency of the excision and the inability to validate the recombinase system4. There are a number of other strategies that can be used in place of, or to complement, conventional gene knockout technology. Two such examples are regulatable gene ablation and temporary gene ablation (gene knock downs). Ablation of a gene can be spatially or temporally regulated, that is only the organ of interest is affected or the mutation occurs only in one particular developmental state5. Through the use of a regulator, the promoter can be regulated to control gene expression in the organ or particular tissue of interest. A gene knockdown refers to the technique by which the expression of one or more of an organisms genes is reduced, either through genetic modification or by treatment with a reagent such as a short DNA or RNA oligonucleotide with a sequence complementary to either an mRNA transcript or a gene6. These approaches offer a rapid and economical method to examine the specific actions of a gene product at a particular time point. Genes can be transiently down-regulate d by targeted blockade of gene expression, either systemically or within a specific tissue. Two such approaches are antisense technology and the use of short interfering RNA (siRNA). Antisense technology is the use of short modified DNA sequences complementary to the mRNA of the gene of interest2. These sequences bind to the 5UTR and the beginning of the coding sequence therefore preventing translation initiation and blocking ribosomal interaction with the AUG start codon2. Antisense oligonucleotide genetic-code blocking drugs might control disease by inhibiting deleterious or malfunctioning genes. siRNA on the other hand, utilizes small lengths of double stranded RNA designed against the gene of interest and is introduced into the cell where they interact with intracellular machinery to form RNA-induced silencing complexes (RISCs)2. These complexes unwind the siRNA strands and allow specific binding to the complementary mRNA sequence2. This binding causes cleavage and destruction o f the now double stranded mRNA, and subsequently prevents translation2. siRNA can be used to study gene function, manipulating gene expression, as well as drug development. siRNA compounds can be created and delivered into human cells were they are able to silence genes and viruses responsible for human diseases. Two other genetic techniques that are used to approach gene investigation include suppressor analysis and reverse genetics. Suppressor analysis is used to identify genes that are functionally related to another gene of interest7. A suppressor mutation is a mutation that counteracts the effects of another mutation thereby reducing its phenotypic effect7. Suppressor mutations may be intragenic (in the same gene as the original mutation) or intergenic (in another gene)7. Intergenic suppressor mutations can be either information suppressors or function suppressors7. Of the two, function suppressors are most valuable for the genetic analysis of cellular processes7. Reverse genetics is a process in which specific mutations are introduced into a cloned gene for the purpose of identifying functional domains8. One way to conduct reverse genetics is to do RNA interference (RNAi)8. RNA interference is an in vivo gene knock-down, which is used to insert a random shRNA construct into the mouse ge nome4. Here, double-stranded RNAs inhibit corresponding gene expression by inducing degradation of its mRNA4. RNAi can be used as part of the immune response to viruses and other genetic material; it can also be used to look at downregulation and upregulation of genes4. RNAi has been used to evaluate whether insulin-like growth factor binding protein-3 (IGFBP3) modulates gastrointestinal stromal tumor (GIST) cell response. Here, transfection of siRNA to knockdown IGFBP3 gene into GIST cells resulted in a significant loss of cell viability and therefore found that IGFP3 gene is required for GIST cell survival. IGFBP3 gene expression is lost in many cancer cells and reintroduction of the protein often results in cell death. On the other hand IGFBP3 has been linked to renal cell carcinoma, breast cancer, and metastatic melanoma, which suggests that IGFBP3 may contribute to tumorigenesis or disease progression. By studying IGFBP3 and the IGF pathway one can explore IGF for prognostic an d therapeutic value in GISTs and other cancers. In order to develop new treatment and preventative strategies for a human disease, we must first understand the biology and pathogenesis of the human disease itself10. A way to study human gene function is by mouse gene humanization. Humanization is the replacement of the murine gene by its human counter part4. Animal models of human disease have been crucial in elucidating normal organ biology, pathogenic mechanisms of the disease and developing new therapeutic strategies10. Animal models are being used instead of human studies, because human studies are limited by a number of factors such as: the variability seen in genetic background and environmental influences, the inability to readily obtain human tissues for molecular analysis and the small numbers of patients who may have a particular genetic abnormality10. Transgenic animals have already made valuable research contributions to studies involving regulation of gene expression, the function of the immune system, genetic diseases, viral diseases, cardiovascular disease, and the genes responsible for the development of cancer. Transgenic animal models are most effective if they have both construct validity and face validity. Construct validity is the degree to which the model corresponds to the clinical state in humans. Face validity is the animal model responds in an appropriate manner to the effects of different therapeutic agents. An animal model that can recapitulate at least part of the neuropathology and the cognitive and behavioral impairment is the most effective representative of the disease. Several rodent models of Alzheimers disease (AD) have been created. The first example of such a model has been created to mimic the cholinergic deficits of AD patients and to investigate the role of the central cholinergic system in the cognit ive and behavioral deficits observed in AD9. The second example of such a model has been created with acute or chronic injections of amyloid beta within the brain parenchyma of rodents, to overexpress AD-related mutated protein (amyloid deposits) in the central nervous system of rodents9. A third model of AD has been to create a transgenic mouse to express wild-type or mutant forms of the human APP and/or PS genes. All three of these models provide many insights into AD pathogenesis and approached to new therapies. By exploring and understanding of the neuropathological processes underlying the cognitive deterioration leading to dementia and investigating of the effects of potential new treatments on both AD neuropathology and cognitive deficits we will be able to test drugs that could potentially alleviate symptoms of the disease. Transgenic animals have also been used to develop animal strains that secrete important proteins in milk2. These animals are used to synthesize recoverable quantities of therapeutically useful proteins. These proteins can be harvested from the animal by simply milking the animal and then using separation techniques for protein purification2. For example cows have been used to purify collagen which can then be used to indicate burns and bone fracture2. Pigs have been used to purify human hemoglobin as a blood replacement for transfusion2. Goats have been used to make monoclonal antibodies for colon cancer2. In addition sheep have been used to make factor VIII and factor IX for hemophilia2. Despite the large amount of knowledge that can be gained by knockout studies, there are some important considerations to be taken when investigating the role of a particular protein or gene of interest. These considerations include but are not limited to: redundancy, lethality, delineating systemic vs. local effects, subtle effects, and specific pathogen free conditions3. Gene redundancy is the existence of multiple copies of the same gene in the genome of an organism. This problem can be overcome to some extent by the use of multiple knockouts or in some situations where multiple ligands bind to the same receptor, a dominant negative receptor approach can knockout the effects of all ligands at once5. Lethality phenotypes severely compromise the ability of the organism to function. Some knockouts are developmentally lethal, which means that the genetically altered embryos cannot grow in adult mice. Knocking out a gene may also fail to produce an observable (phenotypic) change in a mo use or may even produce different characteristics from those observed in humans in which the same gene is inactivated. In some instances, a particular organ of interest can be transplanted into a healthy wild type host in order to conduct the analysis on that organ. Local effect refers to an adverse health effect that takes place at the point or area of contact, for example the respiratory tract11. Systemic effect refers to an adverse health effect that takes place at a location distant from the bodys initial point of contact and assumes absorption has taken place, i.e. absorption into the blood stream11. Subtle effects are those that are so slight as to be difficult to detect or describe. For example, small changes in nutrient delivery to the fetus can program post-natal and adult metabolic status and lead to increased susceptibility to a range of adult onset disease, including stroke, hypertension and non-insulin dependent diabetes5. Specific pathogen free conditions refers to the fact that laboratory mice in research institution are generally housed in a specific pathogen free environment, and are therefore not challenged with the array of pathogens most mice and humans are exposed to. When comparing transgenic models to humans a key difference could be in the initiation of the development or process in the mouse that may not have a similar mechanism as the human development or process it is thought to represent. The presence of a specific mutation in the mouse from the time of its conception may enable a distinction between phenotypic changes due to the mutation itself and changes caused by adaptation and compensation for the mutation12. A gene can also be expressed in different tissues where it may have different functions; its alteration may induce unexpected consequences. Also, the function of two genes may overlap or a mutation in a single gene might not reveal an abnormal phenotype. There is also a possibility of random incorporation into genome, which may inadvertently disrupt other genes, or have a variable degree of gene silencing success. The gene may also induce gross morphologic or physiologic abnormalities that affect the gene directly. Note also, thes e animal models also only play a minor role in drug development, as relatively few human diseases are monogenetic12. In most cases, gene ablation and other genetic techniques must address the basic question as to whether a particular gene, wild type, or mutant is involved in the pathogenesis of a particular disease. If not a particular disease, it may also address whether a gene product which plays a role in a specific signaling process contributes to disease in conjunction with other predisposing conditions. Animal models are crucial in providing a unified understanding of how drugs work, developing new therapeutic agents, and obtaining critical data needed to advance compounds into clinical trails12. Animal models are an important tool for scientist to investigate human diseases, especially in order to conduct time-course studies or when studying early disease. Transgenic and knockout animals are also used to determine the molecular mode of action of a gene product and the downstream consequences of its misexpression on normal processes. Assessing the role of a specific gene can know be accomplis hed through the use of transgenic animals whose genomes have been manipulated to under- or overexpress a target gene, or express it in a modified or defective, nonfunctional form12. Animal models represent an attempt to imitate the pathologies associated with human disease states in a preclinical setting12. References: Molecular Biology of the Cell. Alberts, et. al. 4th edition 2002 Garland Science New York, NY. Crommelin, D.J.A. and Sindelar, R.D. (1997). Pharmaceutical Biotechnology: Fundamentals and Applications, Third Ed. Taylor and Francis. Philadelphia, PA. Seidman, J.G. (2009) Manipulating the Mouse Genome. Current Protocols in Molecular Biology. January 01. Reliable and Innovative Solutions for Transgenesis. Accessed on 11/4/2009. Ingman, WV. And Jones, RL. (2008). Cytokine knockouts in reporduciton: the use of gene ablation to dissect roles of cytokines in reproductive biology. Human Reproductive Update 14(2): 179-192. Gene knockdown. (2009, June 8). In Wikipedia, The Free Encyclopedia. Retrieved 13:53, November 8, 2009, from Fay, D. and Johnson, W. (2006). Genetic mapping and manipulation: Chapter 10-Suppressor mutations. Accessed on 11/5/2009. Bio-Medicine. Accessed on 11/4/2009. Dodart, J.C. and May P. (2005) Overview on Rodent models of Alzheimers Disease. Current Protocols in Neuroscience. November 01. Lind J. and Semsarian C. (2006) Overview of Model Systems for the Analysis of Human Disease. Current Protocols in Human Genetics. February 01. Local vs. Systemic Health Effects. Accessed on 11/3/2009. Moser, P. (2009) Animal Models of Disease. Current Protocols in Pharmacology. September 01. Katz, D.A. (2007) Overview of Pharmacogenetics. Current Protocols in Pharmacology. March 01. Barash, CI. (2001)Ethical Issues in Pharmacogenetics. Accessed on 11/4/2009. Frequently Asked Questions about Pharmacogenetics. Accessed on 11/4/2009. Bustle, O., Jones, K.N., Learish R. D., et.al.(1999) Embryonic Stem Cell-Derived Glial Precursors: A source of Myelinating Transplants. Science 5428(285): 754-756 Piedrahita, J.A., Zhang, S.H, Hagaman, J.R, Oliver, P.M, and Maeda N. (1992) Generation of mice carrying a mutant apolipoprotein E gene inactivated by gene targeting in embryonic stem cells. Proc. Natl. Acad. Sci. USA. 89:4471-4475. Nakashima, Y, Plump AS, Raines E.W, Reslow J.L, and Ross R. (1994) ApoE-deficient mice develop lesions of all phases of atherosclerosis throughout the arterial tree. Arteriosclerosis and Thrombosis 14:133-140. Jang Y.C et.al (2009). Overexpression of Mn Superoxide Dismutase Does Not Increase Life Span in Mice. Journal of Gerontology:Biological Sciences. 64(11): 1114-1125. Dupart JJ. Et.al (2009). Insulin-like growth factor binding protein-3 has dual effects on gastrointestinal stromal tumor cell viability and sensitivity to the anti-tumor effects of imatinib mesylate in vitro. Mol Cancer Nov 10;8(1):99 (Epub ahead of print) PMID: 19903356 Genes associate with drug responses can be grouped into three broad categories: those involved in pharmacokinetics (i.e. drug metabolism, transport), those encoding pharmacological targets (i.e. drug-target pathways) and those with physiological associations (i.e. homeostasis pathways)13. Pharmacokinetic pathways mediate drug absorption, distribution, metabolism and excretion13. Pharmacological pathways such as transcription factors and phosphorylation targets whose genes encode other proteins are also candidates for pharmacogenetic analysis13. Understanding the sensitivity of a particular drug and the genes that encode the drug metabolizing enzymes can help determine how the particular drug is transported and metabolized within the body. Understanding the gene variants and how they influence drug concentrations at the target site is a possible way to explain the differences in response to a particular drug dose among individuals. Pharmacogenetics is the study of how an individuals genetic differences influence drug action, usage and dosing2. The molecular compositions of enzymes are currently being identified through the use of the Human Genome Project. Scientists are able to study these enzymes and determine correlations between genotypic and phenotypic variability14. These current advances will allow scientists to use the molecular knowledge of enzymes to detect individuals who are likely to experience adverse reactions to medicines without having to use potentially dangerous methods of trial and error14. An offshoot of pharmacogenetics is pharmacogenomics, which attempts to understand not only the molecular composition of genetic variants associated with drug response but also the behavior of those variants14. Pharmacogenomic knowledge can be used to spot the disease before it occurs in a patient, increase drug efficacy upon pharmacotherapy, and reduce drug toxicity2. It could also facilitate the drug development process to improve clinical development outcomes, reducing overall cost of drug development and lead to development of new diagnostic tests that impact on therapeutic decisions2. Pharmacogenomics can be used by doctors to identify the optimal dose and medicine for each individual patient with greater efficacy and safety. As the dosage would be based on factors such as age, weight, diet, lifestyle, liver and kidney function. By using a pharmacogenetic test a doctor can determine the right dose for individual patients. There are phomacogenetic tests for cancer, HIV, depressio n, and cardiovascular disease15. These tests take in the factors which are most likely to affect the absorption and effectiveness of the drug. There are many benefits that can come from pharmacogenetics and pharmacogenomics. Pharmaceutical companies can use information obtained to create more powerful medicines based on proteins, enzymes, and RNA molecules associated with genes and diseases15. Again, doctors would be able to analyze a patients genetic profile and prescribe the best available drug therapy from the beginning instead of the standard trial and error method of matching patient with the right drugs. A more appropriate drug dosage could be determined by not only taking in a persons weight and age but also accounting for their individual body processes, such as the time it takes for their body to metabolize the drug. Pharmacogenetics could also provide advance screening for disease, better vaccines, improvements in the drug discovery and approval process and decrease the overall cost of health care15. Pharmacogenomics is still in the development stage in the research field. There are several factors that need to be overcome before many of the pharmacogenomic benefits can be realized. These include the complexity of finding gene variations that affect drug response, the limitation of current drug alternatives, disincentives for drug companies to make multiple pharmacogenomic products, and educating health care providers14. There are also ethical issues to consider, such as lack of data privacy, possibility that adverse reactions to drugs can occur during treatment, the cost of such designer drugs will be to expensive for everyone, and genetic testing can provide an array of diagnostic results (predisposal test) which may or may not be what the patient wants to know14.

Relationship Between Surface Area and Rate Of Reaction Essay -- GCSE C

An Experiment To Investigate The Relationship Between Surface Area and Rate Of Reaction Introduction The rate of reaction (reaction velocity) may be defined as the rate of change of concentration of a stated reactant or product. The rate of a reaction is found by measuring the amount of a reactant used up per unit of time or the amount of a product produced per unit of time. A reaction can be made to go faster or slower by changing a number of factors. In order for a reaction to occur certain things are necessary: particles must collide with each other and the collision must have enough energy for the reaction to occur. If this happens the original bonds are broken and new bonds are formed - so that new products are formed. Successful collisions (those with sufficient energy) can be increased (or decreased) by a number of factors. These key variables consist of temperature, concentration, surface area and use of and type of a catalyst. To examine the relationship between the rate of reaction and surface area I must choose to vary only surface area keeping the other variables constant. Surface area of solid - The surface area has an effect on the rate of reaction. If the solid has a large surface area per unit mass then there are more opportunities for collisions to occur between the solid and liquid. This is because there is more chance for collisions to occur. If the surface area per unit mass is small, collision can only occur with the outer atoms and is therefore limited. The diagram below illustrates this: This relationship is proportional i.e. as one doubles so does the other. The temperature of the reaction - When the temperature is low, the particles in the reaction do not have much energy and move slowly so collision... ...nes which can be explained by the fact that the surface area of the chips was constantly changing throughout the reaction, as it was reacted with the acid, and so did the surface area to volume ratio. Also as the marble was used up the reaction would slow, as there would be less marble remaining to react with the acid reducing the chances of a collision occurring. The evidence is sufficient to imply that my hypothesis is correct but I think to prove it successfully further evidence would be necessary. I could have checked the rates of reactions I produced as a result of my experiment by carrying out a different test. If I had examined my results by doing a test measuring the mass change of the calcium carbonate I could have checked that I came up with sufficiently similar final rates of reaction, however I did not have time for this or to use a wider range of values.

AP European History

However, the Soviet union established a scalded unionism regime that did not adhere to the Ideologies In which communism was oral signally created, which was to serve the masses. This form of communism failed in countries such as P land, Czechoslovakia. And Hungary. The original intent of communism was meant to have a classless society. However, the e soviet communist parties did not actually achieve that. As Molotov Dismissal wrote In The New Class, â€Å"The exclusive, if unwritten, law that only party members can become policeman, officers, diplomats, and only they can exercise actual authority, creates a special privileged group of bureaucrat TTS. The unofficial class of bureaucrats defied the true meaning of communism. Communists rulers cream Ted an illusion that was named communism, but In its basis, was not communism whatsoever. Soviet communists used their privileges to create a class that pushed the everyday cit Zen further down and limited the progress an individual can ma ke. The everyday citizen was force deed to live a life where they wake up, work, go home, eat, and sleep. The citizens were stripped down t o their basic necessities that were sometimes even rejected.Croatian columnist, Slovenia Dreadful , wrote how, Every mother in Bulgaria can point to where communism failed, from the failure of t he planned economy. To the lack of apartments, child care facilities, clothes, disposable diapers, or toilet paper. † The communist did not provide all the necessities for people to live comfortably. Still, kept suppressing the lower class, while the bureaucrats lived comfortably. Communism m was never meant to have a society in which an individual is held back from their necessities. Yet , The soviet communists repressed many necessities and civil rights which included freedom of s beech and public expression.Vocal Have, president of Czechoslovakia, spoke in his New Year's Day Address of 199 how, â€Å"Our country is not flourishing. The great cr eative and spiritual potential of our nation is not being applied meaningfully. † Have perfectly understood that communism withheld a lot of their creativity by not allowing people to freely express themselves. He even mentioned how, â€Å"The state, which calls itself a state of workers, is humiliating and exploiting them instead. † Communist worked pee pole extremely hard for a low wage â€Å"producing things for there is no demand while we are in short o f things we need. †Soviet communists took advantage of the power they had over the citizens and used t hat power to enlarge the gap between leaders of the communist party and the people being ruled According to a Croatian columnist, Slovenia Dramatic, â€Å"the banality of everyday life is where it [communism] really failed, rather than on the level of ideology. † The communist party did not provide enough services for the people which caused the people be opposed to communism. Without the support of th e people, communism was bound to fail. People are what makes the sees once of government. Without people, there would be no government.The Soviet government did not make life or the everyday citizen to feel as though they were being heard or included into all the e decisions that were being made by the government every day. Without a classless society, honest rulers, or support from the ruled, communism in t he Soviet Union set itself up for failure. The citizens of the eastern European socialist states ha d no right to go through life under communist rule by the Soviets. Communism did not improve the e economy, or unify the states. Communism actually did the opposite; it impoverished the countries and s operated the states. AP European History However, the Soviet union established a scalded unionism regime that did not adhere to the Ideologies In which communism was oral signally created, which was to serve the masses. This form of communism failed in countries such as P land, Czechoslovakia. And Hungary. The original intent of communism was meant to have a classless society. However, the e soviet communist parties did not actually achieve that. As Molotov Dismissal wrote In The New Class, â€Å"The exclusive, if unwritten, law that only party members can become policeman, officers, diplomats, and only they can exercise actual authority, creates a special privileged group of bureaucrat TTS. The unofficial class of bureaucrats defied the true meaning of communism. Communists rulers cream Ted an illusion that was named communism, but In its basis, was not communism whatsoever. Soviet communists used their privileges to create a class that pushed the everyday cit Zen further down and limited the progress an individual can ma ke. The everyday citizen was force deed to live a life where they wake up, work, go home, eat, and sleep. The citizens were stripped down t o their basic necessities that were sometimes even rejected.Croatian columnist, Slovenia Dreadful , wrote how, Every mother in Bulgaria can point to where communism failed, from the failure of t he planned economy. To the lack of apartments, child care facilities, clothes, disposable diapers, or toilet paper. † The communist did not provide all the necessities for people to live comfortably. Still, kept suppressing the lower class, while the bureaucrats lived comfortably. Communism m was never meant to have a society in which an individual is held back from their necessities. Yet , The soviet communists repressed many necessities and civil rights which included freedom of s beech and public expression.Vocal Have, president of Czechoslovakia, spoke in his New Year's Day Address of 199 how, â€Å"Our country is not flourishing. The great cr eative and spiritual potential of our nation is not being applied meaningfully. † Have perfectly understood that communism withheld a lot of their creativity by not allowing people to freely express themselves. He even mentioned how, â€Å"The state, which calls itself a state of workers, is humiliating and exploiting them instead. † Communist worked pee pole extremely hard for a low wage â€Å"producing things for there is no demand while we are in short o f things we need. †Soviet communists took advantage of the power they had over the citizens and used t hat power to enlarge the gap between leaders of the communist party and the people being ruled According to a Croatian columnist, Slovenia Dramatic, â€Å"the banality of everyday life is where it [communism] really failed, rather than on the level of ideology. † The communist party did not provide enough services for the people which caused the people be opposed to communism. Without the support of th e people, communism was bound to fail. People are what makes the sees once of government. Without people, there would be no government.The Soviet government did not make life or the everyday citizen to feel as though they were being heard or included into all the e decisions that were being made by the government every day. Without a classless society, honest rulers, or support from the ruled, communism in t he Soviet Union set itself up for failure. The citizens of the eastern European socialist states ha d no right to go through life under communist rule by the Soviets. Communism did not improve the e economy, or unify the states. Communism actually did the opposite; it impoverished the countries and s operated the states.